Live on Skysports 1: Fri 20.00: Leeds Rhinos are 4/9 with Ladbrokes to win away at Hull FC and St Helens are 1/4 at Salford.
St Helens also travel for their second game of the season and they are 1/4 to win at Salford (11/4). Salford are 10/11 for the handicap win in receipt of 10 points.
Wigan remain the 11/8 favourites to win the regular season from St Helens at 10/3. Leeds are 5/1 for the League leaders shield with their opponents Hull FC 50/1 chances.
Alex Donohue of Ladbrokes said: “We expect Leeds & St Helens to justify their odds-on quotes and win on Friday night. Both match and handicap doubles have proven popular so far as punters look to make a winning start to the season.”