The Catalans saw off Arsenal in the Nou Camp to leave bookies and Gunners fans licking their wounds.
David Williams of Ladbrokes said: “It was a bleak night. Messi opening the scoring and a 3-1 scoreline were both lousy results. We’re feeling Arsene Wenger’s pain.”
Real Madrid are the 7/2 second favourites with Chelsea third in at 11/2 narrowly ahead of Manchester United who are 6/1. Spurs are 14/1.