In the County Champs, Nottinghamshire go for a fourth win from four as they host Yorkshire and Lancashire travel to Warwickshire.
Nottinghamshire are currently 2/1 (Betfred) to lift the division title while Durham are 7/2 with . Lancashire have moved into 5/1 with Boylesports.
In Division 2, Middlesex, already 20 points clear after 4 games, are 11/8 with William Hill to finish top, they travel to Gloucestershire.
Wednesday 4 May:
Hampshire v Sussex (11:00 BST)
Nottinghamshire v Yorkshire (11:00 BST)
Somerset v Worcestershire (11:00 BST)
Warwickshire v Lancashire (11:00 BST)
Compare all County Cricket odds and bet at the best price.