Andy Flower’s side are now 5/1 to wrap up the one day series with a 5-0 win, which will put them at the top in all three International rankings.
England and Australia are both chalked up at 10/11 each for victory in the third ODI at Edgbaston next week.
The win for the home side saw in-play punters net £75,000 as every man and his dog wanted a piece of the action.
Jessica Bridge of Ladbrokes told betrescue.com: “In-play punters hit us for six today and we’re anticipating more of the same at Edgbaston.”
Third ODI match betting
Series correct score
England 5-0 5/1
England 4-1 13/8
England 3-2 13/8
Australia 3-2 5/1