Six years ago, Northampton Town claimed a surprise 2-2 draw at Anfield in the League Cup before going through on penalties. The Cobblers have the chance to cause another upset on Wednesday night and the League One side are 10/1 (William Hill) to claim victory.
Manchester United have lost three consecutive matches ahead of this clash, with the Red Devils 1/3 (bet365) to win at the Sixfields although the Red Devils could be vulnerable with a reserve team.
Manchester City are 500/1 with Sky Bet for the quadruple although the best you can get about them winning at the Liberty Stadium is 8/15 (Betway), with Swansea as big as 6/1 (188Bet) after a poor showing at St Mary’s on Sunday.
Meanwhile, Southampton are an even money chance (William Hill) to beat a Crystal Palace side bouncing after beating Stoke, with the Eagles a 16/5 chance (bet365) to claim a third successive win.
Stoke City will hope to land a confidence boost against Hull and the Potters are even money (Ladbrokes) to beat a Tigers team who might have one eye on Saturday’s trip to Anfield.
West Ham entertain Accrington and odds of 4/11 (William Hill) don’t make huge appeal compared to the 11/1 (Paddy Power) that Stanley pull off a shock, with the League Two side likely to have a go at the Olympic Stadium.
|Tuesday 20 September 2016||Home||Draw||Away||BPP|
|AFC Bournemouth v Preston North End (19:45 BST)||7/10||14/5||5||101.75 %|
|Brighton & Hove Albion v Reading (19:45 BST)||1/1||11/4||10/3||100.84 %|
|Derby County v Liverpool (19:45 BST)||13/2||4||4/9||102.00 %|
|Everton v Norwich City (19:45 BST)||8/13||7/2||5||100.79 %|
|Leeds United v Blackburn Rovers (19:45 BST)||6/5||5/2||11/4||100.69 %|
|Leicester City v Chelsea (19:45 BST)||9/4||13/5||11/8||100.65 %|
|Newcastle United v Wolverhampton Wanderers (19:45 BST)||8/11||3||9/2||100.99 %|
|Nottingham Forest v Arsenal (19:45 BST)||11/2||10/3||8/13||100.02 %|
|Wednesday 21 September 2016||Home||Draw||Away||BPP|
|Fulham v Bristol City (19:45 BST)||29/20||5/2||21/10||100.97 %|
|Northampton Town v Manchester United (19:45 BST)||19/2||5||1/3||101.39 %|
|Queens Park Rangers v Sunderland (19:45 BST)||7/4||7/3||9/5||102.06 %|
|Southampton v Crystal Palace (19:45 BST)||1/1||14/5||10/3||99.85 %|
|Swansea City v Manchester City (19:45 BST)||11/2||7/2||8/13||99.34 %|
|West Ham v Accrington Stanley (19:45 BST)||3/10||5||11||101.39 %|
|Stoke City v Hull City (20:00 BST)||1/1||11/4||3||100.76 %|
|Tottenham Hotspur v Gillingham (20:00 BST)||2/9||13/2||16||101.21 %|