Arsenal were well beaten in Italy last week, going down 4-0 to AC Milan and Chelsea could also find themselves tasting defeat against Serie A opposition as they visit Napoli.
The Blues, BetVictor’s 23/10 outsiders, look out-of-sorts at the moment and the pressure is building on boss Andre Villas-Boas, who saw his beleaguered troops struggle to earn an FA Cup replay against Championship outfit Birmingham on Saturday.
By contrast the hosts have registered back-to-back victories domestically, culminating in a 3-0 triumph at Fiorentina last time out and they gleaned four points in the group phase from two matches against Manchester City, form that suggests they should have the measure of a lower-ranked Premier League side.
Arguably the best bet at the Stadio San Paolo however, relates to Napoli striker Edinson Cavani. The Uruguayan bagged a brace on Friday night and also helped himself to all three of his side’s goals against City earlier in the competition. He presents a major threat to Villas-Boas’ men then and is hard to ignore at 6/1 (William Hill) to break the deadlock.
In the evening’s other clash, Spanish league leaders Real Madrid are a banker at 4/9 courtesy of Stan James, to emerge triumphant at CSKA Moscow and Jose Mourinho’s team look decent value to get on top in the first period, Coral pricing them at 5/4 to be in front at the end of each half.